No two people with Lyme disease and co-infections have the same symptom presentation, and people with Lyme disease infections are at various stages of the disease, so no two treatments are the same. However, there are some herbs that are effective for treating Lyme disease at all stages and with all symptom presentations. San lian, Olive Leaf, Corydalis, Sophora Root, Teasel, and Cinnamon Twig are some of the best herbs for Lyme Disease.